Panos was born in Limassol, Cyprus and at the age of 17 moved to London to study musical theatre at Bird College. He then continued his training at Rambert School where he obtained his BA degree in Ballet and Contemporary Dance.
In Israël, Panos worked with Fresco Dance Company, performing works by Michael Getman and Yoram Karmi and spent some time with Inbal Dance Theatre working with the choreographers Mor Shani and Noa Shadur. He collaborated with the choreographer Jason Mabana creating/performing the duet MAMA and with the director Elias Adam and the actress Styliana Ioannou creating/performing the plays Eyolf Machine and Father Help Us.
He also choreographed his own works for dance festivals and theaters. Panos danced for Emma Evelein Dance, X-it Dance Theatre by Fotis Nikolaou, Milena Ugren Koulas, Liliana Barros and Asomates Dynamis Dance Company. He worked at the Festspielhaus St. Pölten in Austria performing Deca Dance by Ohad Naharin and a new creation Ballroom by Shahar Binyamini. His solo Hire me, please received the Young Choreographer Award at the Cyprus Choreography Platform 2019. He has been invited back to continue his research on this work for the CCP 2020. Panos is also working for Compagnie Tabea Martin.
Panos Malactos joined Peeping Tom in 2020 for Triptych: The missing door, The lost room and The hidden floor.